Outer Membrane Vesicles: In vivo Kinetic Biodistribution of Nano-Sized Outer Membrane Vesicles Derived from Bacteria (Small 4/2015)
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چکیده
منابع مشابه
New insight into the application of outer membrane vesicles of Gram-negative bacteria
This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV ...
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Orientia tsutsugamushi, a causative pathogen of Scrub typhus, is a gram-negative intracellular bacterium. Outer membrane vesicles (OMVs) are produced from the membrane of bacteria and play many roles related to the survival of the pathogen. However, there have been no reports confirming whether O. tsutsugamushi indeed produce OMVs. O. tsutsugamushi boryong was cultured in ECV-304 cells for the ...
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Objective(s): Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrheal disease in humans, particularly in children under 5 years and travelers in developing countries. To our knowledge, no vaccine is licensed yet to protect against ETEC infection. Like many Gram-negative pathogens, ETEC can secrete outer membrane vesicles (OMVs). These structures contain various immunogenic vi...
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Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as triggers of innate immunity upon carriage of ...
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Neisseria meningitidis (Nm) causes potentially fatal bacterial sepsis and meningitis in susceptible individuals, but induces protective immunity in asymptomatic carriers. Nm naturally sheds outer membrane vesicles (NOMVs) that contain a high proportion of lipopolysaccharide (LPS) and outer membrane proteins. NOMVs are known to induce serum bactericidal antibodies in mice and humans, but their i...
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ژورنال
عنوان ژورنال: Small
سال: 2015
ISSN: 1613-6810
DOI: 10.1002/smll.201570020